Prof. RNDr. František Vyskočil, DrSc.
Funkční zařazení: profesor
Výuka (odkaz do SISu)
Vědecké zaměření
fyziologie synapsí a nervosvalového přenosu, neurofarmakologie, srovnávací neurofyziologie, chemicky řízené iontové kanály, kvantový a nekvantový výlev acetylcholinu; popularizace vědy v českých médiích
Vybrané publikace za posledních 5 let
Malomouzh AI, Nikolsky EE, Vyskočil F (2011) Purine P2Y receptors in ATP-mediated regulation of non-quantal acetylcholine release from motor nerve endings of rat diaphragm. Neurosci. Res. 71(3):219-225.
Nurullin LF, Mukhitov AR, Tsentsevytsky AN, Petrova NV, Samigullin DV, Malomouzh AI, Bukharaeva EA, Vyskočil F, Nikolsky EE (2011) Voltage-dependent P/Q-type calcium channels at the frog neuromuscular junction. Physiol. Res. 60(5):815-823.
Malomouzh AI, Arkhipova SS, Nikolsky EE, Vyskočil F (2011) Immunocytochemical demonstration of M(1) muscarinic acetylcholine receptors at the presynaptic and postsynaptic membranes of rat diaphragm endplates. Physiol. Res. 60(1):185-188.
Kaniaková M, Lindovský J, Krůšek J, Adámek S, Vyskočil F (2011) Dual effect of lobeline on α4β2 rat neuronal nicotinic receptors. Eur. J. Pharmacol. 658(2-3):108-113.
Petrov KA Yagodina LO, Valeeva GR, Lannik NI, Nikitashina AD, Rizvanov AA, Zobov VV, Bukharaeva EA Reznik VS, Nikolsky EE, Vyskocil F (2011) Different sensitivities of rat skeletal muscles and brain to novel anti-cholinesterase agents, alkylammonium derivatives of 6-methyluracil (ADEMS). Br. J. Pharmacol. 163(4):732-744.
Volkov EM, Nurullin LF, Volkov ME, Nikolsky EE, Vyskočil F (2011) Mechanisms of carbacholine and GABA action on resting membrane potential and Na+/K+-ATPase of Lumbricus terrestris body wall muscles. Comp. Biochem. Physiol. A Mol. Integr. Physiol. 158(4):520-524.
Adámek S, Vyskočil F (2011) Potassium-selective microelectrode revealed difference in threshold potassium concentration for cortical spreading depression in female and male rat brain. Brain Res. 1370:215-219.
Adámek S, Shakirzyanova AV, Malomouzh AI, Naumenko NV, Vyskočil F (2010) Interaction of glutamate- and adenosine-induced decrease of acetylcholine quantal release at frog neuromuscular junction. Physiol. Res. 59(5):803-810.
Vyskocil F, Malomouzh AI, Nikolsky EE (2009) Non-quantal acetylcholine release at the neuromuscular junction. Physiol. Res. 58(6):763-784.
Shaihutdinova AR, Nikolsky EE, Vyskocil F, Skorinkin AI (2009) Mechanisms of the inhibition of endplate acetylcholine receptors by antiseptic chlorhexidine (experiments and models). Naunyn Schmiedebergs Arch. Pharmacol. 380(6):551-560.
Tyapkina O, Volkov E, Nurullin L, Shenkman B, Kozlovskaya I, Nikolsky E, Vyskocil F (2009) Resting membrane potential and Na+,K+-ATPase of rat fast and slow muscles during modeling of hypogravity. Physiol. Res. 58(4):599-603.
Petrov K, Kovyazina I, Zobov V, Bukharaeva E, Nikolsky EE, Vyskocil F (2009).Different sensitivity of miniature endplate currents in rat external and internal intercostal muscles to the acetylcholinesterase inhibitor C-547 as compared with diaphragm and extensor digitorum longus. Physiol. Res. 58(1):149-153.
Skorinkin AI, Shaihutdinova AR, Vyskocil F (2008) Model of concentration changes across the synaptic cleft during a single quantum release. Gen. Physiol. Biophys. 27(1):19-24.
Gilmanov IR, Samigullin DV, Vyskocil F, Nikolsky EE, Bukharaeva EA (2008)Modeling of quantal neurotransmitter release kinetics in the presence of fixed and mobile calcium buffers. J. Comput. Neurosci. 25(2):296-307.
Lindovský J, Kaniaková M, Svobodová L, Vyskocil F, Krůsek J (2008) Role of negatively charged amino acids in beta 4 F-loop in activation and desensitization of alpha 3 beta 4 rat neuronal nicotinic receptors. Biochim. Biophys. Acta 1778(4):864-871.
Vyskocil F (2008) Regulation and significance of non-quantal acetylcholine release at neuromuscular synapse. Cesk. Fysiol. 57(4):123-132. Review.
Vyskocil F (2008) Nature of non-quantal acetylcholine release at neuromuscular synapse. Cesk. Fysiol. 57(2-3):83-90. Review.
Akce dokumentů