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Laboratory of 3D Imaging and Analytical Methods

Our laboratory focuses on the analysis of shape of biological objects in the context of morphometry, biology and medicine. Our research is applicable in anthropology, orthodontics, plastic surgery and many other fields. To that end, the laboratory is equipped with surface scanners and software.

Morphological comparison of organisms, studies of variability of size and shape, norms and pathologies are hot topics in many biological and medicinal areas. Mere descriptive analysis no longer suffices and is quickly replaced by quantified results. Classic morphometry (biometry) is currently supplemented and in many studies surpassed by geometric morphometry. The use of modern imaging methods for the creation of 3D models allows for the building of virtual databases of structural and developmental defects, unique fossils, comparative sets or pathologies and their storage without degradation on computer media. Moreover, their use for further analyses is also possible.

The analysis of 3D models can be carried out using methods of both classic and geometric morphometry. The novel methodological approach allows for a detailed study of growth and development of skull, its shape- and size-related changes in temporal and geographical context, the tracking of skeletal deviations or intracranial relations in patients with craniofacial malformations, the reconstruction of facial soft tissues and a plethora of other topics. The study of morphology has many uses, for instance the objective evaluation of facial malformation treatment effects, the dependence of function on shape, such as speech defects in patients with cleft lip based on palatal shape. In addition to the above, there is tremendous use of our equipment in forensic anthropology and sociocultural anthropology, for instance in the studies of attractiveness and facial mimics, behavioral signs…

The tools of 3D imaging and analytical methods, including geometric morphometry are most often used in paleoanthropology and bioarchaeology. They contribute to the solutions in topics of macroevolutionary and microevolutionary changes, diachronic trends, biomechanics or to the evaluation of pathological changes in fossil or historical skeletal material.

In our laboratory, we handle both biomedicinal and forensic topics. We also focus on diachronic changes of selected skull sets from upper Paleolithic through early middle ages to recent identified collections or RTG images of current population. The studied phenomena also include stress effects (Harris lines, asymmetry, some pathological processes) on identified collections of postcranial skeletons. These and other indicators of stress have been used in a complex estimation of economic and social relations in a given population and historical period.

Research areas:
Bioarchaeology of Slavs from Mikulčice
Facial development in patients with craniofacial malformations
Forensic anthropology

Equipment:
3D surface scanners
Software
Morphome3cs

Lab Team

Head of Laboratory:
doc. RNDr. Jana Velemínská, Ph. D.

Researchers:
prof. RNDr. Jaroslav Brůžek, CSc.
RNDr. Šárka Bejdová, Ph.D.
Mgr. Ján Dupej

Ph. D.  students:
Mgr. Markéta Čechová
Mgr. Eva Hoffmannová
Mgr. Alexandra Ibrová
Mgr. Lenka Jaklová
Mgr. Karolina Kočandrlová
Mgr. Anežka Kotěrová
Mgr. Jana Koudelová
Mgr. Barbora Musilová
Mgr. Rebeka Rmoutilová
Mgr. Eliška Zazvonilová
Mgr. Pavla Zedníková Malá

Pregradual students:
Bc. Michala Forinová
Bc. Nikola Fleischmannová
Bc. Tereza Jungvirtová
Bc. Aneta Kodytková
Bc. Tereza Korbelová
Bc. Lenka Letošníková
Bc. Tomáš Moravec
Bc. Kateřina Piskačová
Bc. Vojtěch Rieger
Bc. Lada Šťovíčková
Bc. Tomáš Thon
Bc. Zuzana Valíková
Bc. Radka Vasilková

Cooperation:
MUDr. Jiří Borský, Ph.D. (FN Motol)
prof. MUDr. Tatjana Dostálová, DrSc., MBA (2.LF UK)
RNDr. Václav Krajíček, Ph.D. (MFF UK)
Mgr. Veronika Moslerová, Ph.D. (FN Motol)
RNDr. Josef Pelikán (MFF UK)
doc. MUDr. Miroslav Peterka, CSc., DSc (ÚEM AV ČR)

Publications

Lacoste Jeanson, A., Santos, F., Villa, C., Banner, J., & Brůžek, J. (2018). Architecture of the femoral and tibial diaphyses in relation to body mass and composition: Research from whole‐body CT scans of adult humans. American Journal of Physical Anthropology, doi: 10.1002/ajpa.23713

Kotěrová, A., Velemínská, J., Cunha, E., & Brůžek, J. (2018). A validation study of the Stoyanova et al. method (2017) for age-at-death estimation quantifying the 3D pubic symphyseal surface of adult males of European populations. International Journal of Legal Medicine, doi: 10.1007/s00414-018-1934-1.

Rmoutilová, R., Guyomarc’h, P., Velemínský, P., Šefčáková, A., Samsel, M., Santos, F., Maureille, B., & Brůžek, J. (2018). Virtual reconstruction of the Upper Palaeolithic skull from Zlatý Kůň, Czech Republic: Sex assessment and morphological affinity. PloS one, 13(8), e0201431.

Velemínská, J., Danková, S., Břízová, M., Červenková, L., & Krajíček, V. (2018). Variability of facial movements in relation to sexual dimorphism and age: three-dimensional geometric morphometric study. Homo - Journal of Comparative Human Biology, 69(3), 110–117.

Cvrček, J., Velemínský, P., Dupej, J., Vostrý, L., & Brůžek, J. (2018). Kinship and morphological similarity in the skeletal remains of individuals with known genealogical data (Bohemia, 19th to 20th centuries): A new methodological approach. American Journal of Physical Anthropology, 167(3), 541–556.

Kotěrová, A., Navega, D., Štěpánovský, M., Buk, Z., Brůžek, J., & Cunha, E. (2018). Age estimation of adult human remains from hip bones using advanced methods. Forensic Science International, 287, 163–157. 

Kacki, S., Velemínský, P., Lynnerup, N., Kaupová, S., Jeanson, A. L., Povýšil, C., Horák, M., Kučera, J., Rasmussen, K.L., Podliska, J., Dragoun, Z, Smolík, J., Vellev, J., & Brůžek, J. (2018). Rich table but short life: Diffuse idiopathic skeletal hyperostosis in Danish astronomer Tycho Brahe (1546-1601) and its possible consequences. PloS one13(4), e0195920.

Kaupová, S., Velemínský, P., Herrscher, E., Sládek, V., Macháček, J., Poláček, L., & Brůžek, J. (2018). Diet in transitory society: isotopic analysis of medieval population of Central Europe (ninth–eleventh century AD, Czech Republic). Archaeological and Anthropological Sciences, 10(4), 923–942.

Lacoste Jeanson, A., Santos, F., Dupej, J., Velemínská, J., & Brůžek, J. (2018). Sex-specific functional adaptation of the femoral diaphysis to body compositionAmerican Journal of Human Biology, e23123.

Hoffmannová, E., Moslerová, V., Dupej, J., Borský, J., Bejdová, Š., & Velemínská, J. (2018) Three-dimensional development of the upper dental arch in unilateral cleft lip and palate patients after early neonatal cheiloplasty. International Journal of Pediatric Otorhinolaryngology, 109, 1–6.

Moslerová, V., Dadáková, M., Dupej, J., Hoffmannová, E., Borský, J., Černý, M., Kočandrlová, K., & Velemínská, J. (2018). Three-dimensional assessment of facial asymmetry in preschool patients with orofacial clefts after neonatal cheiloplasty. International Journal of Pediatric Otorhinolaryngology, 108, 40–45.

Bejdová, Š., Dupej, J., Velemínská, J., & Velemínský, P. (2018). Stability of upper face sexual dimorphism in Central European populations (Czech Republic) during the Modern Age. International Journal of Legal Medicine, 132, 321–330. (IF 2,714) 

Zedníková Malá, P., & Velemínská, J. (2018). Eyeball position in facial approximation: accuracy of methods for predicting the globe position in lateral view. Journal of Forensic Sciences, 63, 221–226. (IF 1,16)

Zedníková Malá, P., Krajíček, V.,  & Velemínská, J. (2018). How tight is the relationship between the skeletal and soft-tissue facial profile: A geometric morphometric analysis of the facial outline. Forensic Science International, 292, 212-223.

Štepanovský, M., Ibrová, A., Buk, Z., & Velemínská, J. (2017). Novel age estimation model based on development of permanent teeth compared with classical approach and other modern data mining methods. Forensic Science International, 279, 72–82. (IF 1,989)

Ibrová, A., Dupej, J., Stránská, P., Velemínský, P., Poláček, L., & Velemínská, J. (2017). Facial skeleton asymmetry and its relationship to mastication in the Early Medieval period (Great Moravian Empire, Mikulčice, 9th-10th century). Archives of Oral Biology, 84, 64–73. (IF 1,748)

Rmoutilová, R., Dupej, J., Velemínská, J., & Brůžek, J. (2017). Geometric morphometric and traditional methods for sex assessment using the posterior ilium. Legal Medicine, 26, 52–61. (IF 1,442)

Kotěrová, A., Velemínská, J., Dupej, J., Brzobohatá, H., Pilný, A., & Brůžek, J. (2017). Disregarding population-specificity: its influence on the sex assessment methods from the tibia. International Journal of Legal Medicine, 131, 251–261. (IF 2,862)

Brzobohatá, H., Krajíček, V., & Velemínská, J. (2016). Sexual Dimorphism of the Human Tibia through Time: Insights into Shape Variation using a Surface-based Approach. PLoS ONE, 11, e0166461. (IF 3,54)

Brzobohatá, H., Krajíček, V., Horák, Z., Sedlak, P., & Velemínská, J. (2016). Diachronic changes in size and shape of human proximal tibia in Central Europe during the latest 1200 years. Homo - Journal of Comparative Human Biology, 67, 433–446. (IF 0,579)

Musilová, B., Dupej, J., Velemínská, J., Chaumoitre, K., & Brůžek, J. (2016). Exocranial surfaces for sex assessment of the human skull. Forensic Science International, 269, 70–77. (IF 1,95)

Hoffmannová, E., Bejdová, Š., Borský, J., Dupej, J., Cagáňová, V., & Velemínská, J. (2016). Palatal growth in complete unilateral cleft lip and palate patients following neonatal cheiloplasty: classic and geometric morphometric assessment. International Journal of Pediatric Otorhinolaryngology, 90, 71–76. (IF 1,125)

Dadáková, M., Cagáňová, V., Dupej, J., Hoffmannová, E., Borský, J., & Velemínská, J. (2016). Three-dimensional evaluation of facial morphology in pre-school cleft patients following neonatal cheiloplasty. Journal of Cranio-Maxillo-Facial Surgery, 44, 1109–16. (IF 1,592)

Guyomarc'h, P., Velemínská, J., Sedlak, P., Dobisíková, M., Švenkrtová, I., & Brůžek, J. (2016). Impact of secular trends on sex assessment evaluated through femoral dimensions from the Czech population. Forensic Science International, 262, 284.e1–6.  (IF 1,95)

Zedníková Malá, P., & Velemínská J. (2016). Vertical lip position and thickness in facial reconstruction: a validation of commonly used methods for predicting the position and size of lips. Journal of Forensic Sciences, 61, 1046–54. (IF 1,322)

Drgáčová, A., Dupej, J., & Velemínská, J. (2016). Facial soft tissue thicknesses in the present Czech population. Forensic Science International, 260, 106.e1–106.e7. (IF 1,95)

Trefný, P., Krajíček, V., & Velemínská, J. (2016). Three-dimensional analysis of palatal shape in patients treated with SARME using traditional and geometric morphometrics. Orthodontics & Craniofacial Research, 19, 18–27. (IF 1,64)

Mydlová, M., Dupej, J., Koudelová, J., & Velemínská, J. (2015). Sexual dimorphism of facial appearance in aging human adults: A cross-sectional studyForensic Science International, 257, 518.e1–518.e7. (IF 2,140)

Koudelová, J., Brůžek, J., Cagáňová, V., Krajíček, V., & Velemínská, J. (2015). Development of facial sexual dimorphism in children between 12 to 15 years: three-dimensional longitudinal study. Orthodontics & Craniofacial Research, 18, 175–84. (IF 1,64)

Koudelová, J., Dupej, J., Brůžek, J., Sedlak, P., & Velemínská, J. (2015). Modelling of facial growth in Czech children based on longitudinal data: Age progression from 12 to 15 years using 3D surface models. Forensic Science International, 248, 33–40. (IF 2,140)

Mesteková, S., Brůžek, J., Veleminská, J., & Chaumoitre, K. (2015). A Test of the DSP sexing method on CT images from a modern French sample. Journal of Forensic Sciences, 60, 1295–1299. 

Brzobohatá, H., Krajíček, V., Horák, Z., & Velemínská, J. (2015). Sex determination of humans using tibia shape, size and a population-specific approach. Journal of Forensic Sciences, 60, 29–40.

Dupej, J., Krajíček, V., & Pelikán, J. (2015). Low-rank matrix approximations for Coherent point driftPattern Recognition Letters, 52, 53–58.

Brzobohatá, H., Krajíček, V., Velemínský, P., Poláček, L., & Velemínská, J. (2014). The shape variability of human tibial epiphyses in an Early Medieval Great Moravian population (9th -10th century AD): a geometric morphometric assessmentAnthropologischer Anzeiger, 71, 219–236.

Rusková, H., Bejdová, Š., Peterka, M., Krajíček, V., & Velemínská, J. (2014). 3-D shape analysis of palatal surface in patients with unilateral  complete cleft lip and palateJournal of Cranio-Maxillo-Facial Surgery, 42, e140–e147.

Cagáňová, V., Borský, J., †Šmahel, Z., & Velemínská, J. (2014). Facial growth and development in unilateral cleft lip and palate after secondary alveolar bone grafting: a comparative studyThe Cleft Palate-Craniofacial Journal, 51, 15–22.

Velemínská, J. Pilný, A., Čepek, M., Koťová, M., & Kubelková, R. (2013). Dental age estimation and different predictive ability of various tooth types in the Czech population: data mining methodsAnthropologischer Anzeiger, 15, 331–345.

Bejdová, Š., Krajíček, V., Velemínská, J., Horák, M., & Velemínský, P. (2013). The variability of sexual dimorphism of the mandible. Homo - Journal of Comparative Human Biology, 64, 437–453.

Velemínská, J., Krajíček, V., Dupej, J., Gómez-Valdés, J. A., Velemínský, P., Šefčáková, A., Sánchez-Mejorada, G., Pelikán, J., & Brůžek, J. (2013). Geometric morphometrics and sexual dimorphism in the greater sciatic notch of adults from two skeletal collections: the accuracy and reliability of sex classificationAmerican Journal of Physical Anthropology, 152,558–65.

Bigoni, L., Krajíček, V., Sládek, V., Velemínský, P., & Velemínská, J. (2013). Skull shape asymmetry and the socioeconomic structure of Early Medieval Central European societyAmerican Journal of Physical Anthropology, 150, 349–364.

Brzobohatá, H., Prokop, J., Horák, M., Jančárek, A., & Velemínská, J. (2012). Accuracy and benefits of 3D bone surface modelling: a comparison of two methods of surface data acquisition reconstructed by laser scanning and computed tomography outputsCollegium Anthropologicum, 36, 801–6.

Borský, J., Velemínská, J., Jurovčík, M., Kozak, J., Hechtová, D., Tvrdek, M., Cerny, M., Kabelka, Z., Fajstavr, J., Janota, J., Zach, J., Peterková, R., & Peterka, M. (2012). Successful early neonatal repair of cleft lip within first 8 days of life. International Journal of Pediatric Otorhinolaryngology, 76, 1616–26.

Gómez-Valdés, J. A., Quinto-Sánchez, M., Menéndez Garmendia, A., Velemínská, J., Sánchez-Mejorada, G., & Brůžek, J. (2012).  Comparison of methods to determine sex by evaluating the greater sciatic notch: visual, angular and geometric morphometricsForensic Science International, 221, 156.e1–7.

Peterka, M., Hrudka, J., Spoutil, F., Veleminska, J., Panczak, A., Borsky, J.,  Likovsky, Z., & Peterkova, R. (2012). Extension of orofacial cleft and vaginal bleeding in early pregnancy. Acta chirurgiae plasticae, 54, 39–44.

Krajíček, V., Dupej, J., Velemínská, J., & Pelikán, J. (2012). Morphometric Analysis of Mesh AsymmetryJournal of WSCG, 20, 65–72.

Velemínská, J., Dostálová, T., Müllerová, Ž., Kašparová, M., Cagáňová, V., & Peterka, M. (2012). Influence of therapy on the development of maxila in two orofacial cleft patients: 3-D longitudinal evaluation. Slovenská Antropológia, 15, 57–64.

Brůžek, J., Guyomarch, P., Velemínská, J., Švenkrtová, I., Chaumoitre, K., Mesteková, Š., & Dobisíková, M. (2012). Impact of secular trends on the reliability of sex assessment methods from the skeleton: contribution of the virtual anthropologySlovenská Antropológia, 15, 1–4.

Velemínská, J., Bigoni, L., Krajíček, V., Borský, J., Šmahelová, D., Cagáňová, V., & Peterka, M. (2012). Surface facial modelling and allometry in relation to sexual dimorphism. Homo - Journal of Comparative Human Biology, 63, 81–93.

Bejdová, Š., Krajíček, V., Peterka, M., Trefný, P., & Velemínská, J. (2012). Palatal shape and size variability in patients with bilateral complete cleft lip and palate using dense surface model construction and 3-D geometric morphometrics. Journal of Cranio-Maxillo-Facial Surgery, 40, 201–208.

Ivanov, Ch., Velemínská, J., Dostálová, T., & Foltán, R. (2011). Adolescent patient with bilateral crossbite treated with surgically assisted rapid maxillary expansion: a case report evaluated by the 3D laser scanner, and using FESA method. Prague Medical Report, 112, 305–315.

Šefčáková, A., Katina, S., Velemínská, J., Brůžek, J., Velemínský, P., & Thurzo, M. (2011). Size factor as one of the problems in the sex estimation of skulls: Upper Palaeolithic sample from Predmosti (Czech Republic) as an exampleAnthropologisher Anzeiger, 68, 221–237.

Procházková, L., Pelikán, J., & Velemínská J. (2010). Hodnocení asymetrie obličeje dospělé české populace: 3D studieSlovenská antropológia, 13, 44–49.

Nehasilová, L., Pelikán, J., Velemínská, J., Velemínský, P., & Brůžek, J. (2010). Pohlavní dimorfismus tvaru incisura ischiadica major pánevní kosti člověka: aplikace 2D geometrické morfometrie pro potřeby identifikace ve forenzní antropologii a bioarcheologii. Slovenská antropológia, 13, 36–39.

Chvojková, M., Krajíček, V., & Velemínská J. (2010). Kraniometrická variabilita historických populací z oblasti Údolí Nilu. Slovenská antropológia, 13,19–23.

Cagáňová, V., Šmahel, Z., & Velemínská, J. (2010). Pohlavní dimorfismus kraniofaciální oblasti u pacientů s jednostranným rozštěpem rtu a patra ve věku 10 let. Slovenská antropológia, 13, 10–15.

Bejdová, Š., Velemínská, J.,  Bejda, P.,  & Velemínský, P. (2010). Tvar dolní čelisti u velkomoravské populace za využití metod 3-D geometrické morfometrie. Slovenská antropológia, 13, 1–5.

Bigoni, L., Velemínská, J., & Brůžek, J. (2010). Three-dimensional geometric morphometric analysis of cranio-facial sexual dimorphism in a Central European sample of known sex. Homo - Journals of Comparative Human Biology, 61, 16–32.

Šmahel, Z., Velemínská, J., Trefný, P., & Müllerová, Ž. (2009). Three-dimensional morphology of the palate in patients with bilateral complete cleft lip and palate at the stage of permanent dentition. The Cleft Palate-Craniofacial Journal, 46, 399–408.

Velemínská, J., & Brůžek, J. (Eds.) (2008). Early Modern Humans from Předmostí near Přerov. A new reading of old documentation. Praha: Academia.

Kujanová, M., Bigoni, L., Velemínská, J., & Velemínský, P. (2008). Limb bones asymmetry and stress in medieval and recent populations of Central EuropeInternational Journal of Osteoarchaeology, 18, 476–491.

Šefčáková, A., Katina, S., Brůžek, J., Velemínská, J., & Velemínský, P. (2008). Neskoromladopaleolitická lebka z Moče (južné Slovensko): porovnanie s recentnou populáciou pomocou geometrickej morfometrie. Acta Rerum Naturalium Musei Nationalis Slovaci, 54, 75–86.

Velemínská, J., Brůžek, J., Velemínský, P., Bigoni, L., Šefčáková, A., & Katina, S. (2008). Variability of the Upper Palaeolithic skulls from Předmostí near Přerov (Czech Republic): craniometric comparison with recent human standards. Homo - Journal of Comparative Human Biology, 59, 1–26.

Kujanová, M., Bigoni, L., Velemínská, J., & Velemínský, P. (2008). Skeletal Asymmetry of Locomotor Apparatus at Great Moravian Population. In: Velemínský, P., & Poláček, L. (Eds.) Studien zum Burgwall von Mikulčice, VIII, Spisy AÚ AV ČR Brno, 27, pp. 177–208.

Velemínský, P., Stránská, P.,  Dobisíková, M., & Velemínská, J. (2008). Biological Diversity of Non-metric Traits in the Great Moravian Population – the Comparison of the Mikulčice Power Centre and its Hinterland. In: Velemínský, P., & Poláček, L. (Eds.), Studien zum Burgwall von Mikulčice, VIII, Spisy AÚ AV ČR Brno, 27, pp. 265–304.

Žaloudková, M., Bigoni, L., Velemínská, J., & Velemínský, P. (2008). Locomotor apparatus asymmetry – how the medieval population (9th–12th century) differed from the recent population of Central Europe. International Journal of Osteoarchaeology, 18, 476-491.

Likovský, J., Velemínský, P., Poláček, L., & Velemínská, J. (2008). Frequency of Fractures of the Locomotor Apparatus at the Burial Sites in the Area of the Castle in Mikulčice. In: Velemínský, P., & Poláček, L. (Eds.), Studien zum Burgwall von Mikulčice, VIII, Spisy AÚ AV ČR Brno, 27, pp. 235–264.

Stránská, P., Velemínský, P., & Velemínská, J. (2008). The state of dentition in the Great Moravian population. In: Velemínský, P., & Poláček, L. (Eds.), Studien zum Burgwall von Mikulčice, VIII, Spisy AÚ AV ČR Brno, 27, pp. 121–140.

Velemínská, J., Velemínský, P., Bigoni, L., & Jantač, M. (2008).  Craniometric analysis of the Great Moravian population from Mikulčice: X-ray films study. In: Velemínský, P., & Poláček, L. (Eds.), Studien zum Burgwall von Mikulčice, VIII, Spisy AÚ AV ČR Brno, 27, pp. 93–120.

Velemínský, P., Likovský, J., Trefný, P., Dobisíková, M., Velemínská, J., Poláček, L., & Hanáková, H. (2005). Großmährisches Gräberfeld auf „Kostelisko“ im Suburbium des Mikulčicer Burgwalls. Demographie, Spuren nicht spezifischer Belastung physiologischen und physischen Charakters auf Skeletten, Gesundheitszustand. In: Poláček, L. (Ed.), Studien zum Burgwall von Mikulčice, Band VI, Spisy AÚ AV ČR Brno, pp. 539–633.

Stránská, P., & Velemínská, J. (1999). Keltové a antropologie. In: Waldhauser, J. (Ed),  Jak se kopou keltské hroby. Lidové noviny, Praha, pp. 133–154.

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