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New calls for postdoc applicants open

We are looking for prospective international, non czech citizens, post-docs for research within a specific field of biology, chemistry and geography. Deadline for applications is July 20th, 2022.

Conditions and eligibility:

  • non czech resident
  • no more than 5 years from Ph.D. completion
  • completed Ph.D. (for sumbission)
  • not qualified for professorship

Offer:

  • 2 years full-employment (funding)
  • required enviroment for work 

Terms:

  • July 20th, 2022 - deadline for applications
  • October 2022 - final results
  • January 1st, 2023 - research start
  •  

New call for postdoc applicants open within a fields of: 

 

BIOLOGY

1. Analysis and comparison of the importance of Src in bone formation of higher vertebrates
The main research objective of this project is the elucidation of the role of Src in osteoclasts and the comparison of the specific role of Src in bone formation and osteoclast physiology between mammals and birds. The research will focus on description of the role of Src in bone formation in vivo and on osteoclasts physiology in vitro.
All information can be find here.


2. Curse or blessing? Evolutionary significance of adaptive introgression in whole genome duplication.​
Here, we aim to determine genomic signatures of the action of selection during inter-ploidy introgression in seven plant species varying in ploidy, i.e. cases of incipient polyploid speciation. We will test the hypothesis that selection promotes inter-ploidy introgression in certain genomic regions while it operates against gene flow in different parts of the genome. 
All information can be find here.


3. Evolutionary basis of auxin perception in green lineage
the aims of this postdoc project are the following. First, the candidate will focus on the analysis of the dynamics of rapid responses of both early and late diverging streptophyte algae and selected bryophytes to the phytohormone auxin. In particular, growth and physiological responses (ion fluxes), as well as subcellular responses (such as calcium transients), will be monitored. Further, the task will be to address the physiological relevance of such responses for the particular organism. Finally, the signalling pathway underlying such responses will be reconstructed using bioinformatic evo-devo and proteomic approaches.
All information can be find here.


4. Evolutionary significance of the germ-line restricted chromosome in songbirds
The aim of this project will be to determine the essential function of the GRC for songbirds and study its potential role in speciation in two model systems: (i) two closely related species of nightingales (Luscinia sp.) and (ii) multiple estrildid finches of the genus Lonchura. The selected candidate can utilize whole-chromosome GRC assemblies for these species, which we have generated during our ongoing research on the GRC. In addition, we will generate single-cell transcriptomic data from embryotic tissues and gonads to study the GRC gene expression during ontogeny. 
All information can be find here.


CHEMISTRY 

​1. New Chemical Tools for Biological Profiling of Underexplored Imine-Based Post-Translational Modifications
The aim of the proposal is the development of a chemical probe for selective labeling of imines in proteomes and the identification of specific proteins and metabolites involved. The design relies on the chemical reaction of imines with organic phosphites that generates a covalent adduct that can be further processed. Such a tool would enable fundamental insight into the metabolic surveillance of immune system that has also a significant translational potential.
All information can be find here.


2. Synthesis of selagibenzophenone B derivatives as candidates for selective anti-prostate cancer drugs, with novel mode of action.
The proposed symmetrical as well as non-symetrical derivatives will be prepared in the laboratory of the applicant by the postdoc and evaluated for the cytotoxic properties in the laboratory of collaborator (prof. Tugba Tumer). The inhibitory properties towards the identified targets will be evaluated. The role of the dual inhibitory effect on the selective cytotoxicity will be examined.
All information can be find here.


GEOGRAPHY

​1.Is anthropogenic climate change or climate variability to be blamed for the recent central European precipitation deficit?
The proposed project will consist of four major tasks: 
- Identification and spatio-temporal localization of the precipitation deficit; that is, finding the area, period (years), and part of year where and when the deficit occurred. 
- Framing the precipitation deficit in a wider context. Impacts of the precipitation deficit on hydrosphere and biosphere, that is, induced hazards in terms of hydrological and agricultural drought will be described and quantified. 
 - Analysis of suitable characteristics of atmospheric circulation and of their potential contribution to the precipitation deficit in observed data. 
 - Context with anthropogenic climate change. 
All information can be find here. 



 

 

Published: Jun 17, 2022 01:10 PM

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