Scientific interests
Capillary electrophoresis
Electrophoresis finds its applications in identification and quantification of inorganic ions, organic compounds used in agrochemistry, food chemistry or pharmacology, as well as the analysis of complex biomolecules such as proteins up to the DNA. |
Electrokinetic chromatography & Chiral separations
If the selector provides a chiral recognition, it makes the EKC mode well applicable to chiral separations. The identification and quantification of chiral compounds is of high interest in practice. In spite of the undifferentiable 2D structures of the two enantiomers of a chiral compound, their 3D structure gives them inherently diverse biological and pharmacological impacts. |
Physical-chemical measurements
The determined physical-chemical paramaters give us information about the studied compounds and their interaction with selectors. Additionally, once measured, the parameters can be reutilised for intelligent method optimisation for complex mixtures of analytes. |
Mathematical descrition of the studied systems
Mathematical analysis of the governing equations leads to the generalised conclusions about the electrophoretic motion in its various modes. Numerical solution of the equations, involving computer simulations, additionaly provides a detail insight into the electromigration processes. Both the mathematical analysis and computer simulations help in designing novel electromigration separation strategies. Just as helpful are they for analytical method deveopment and optimisation of separation conditions. |
Software development
The software can be downloaded as freeware from the group of Electromigration and Chromatographic Separation Methods |
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