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Curbing Candida: The Cells That Keep Fungal Infections at Bay

Of all the fungi that live in the human body, the most infamous is probably the yeast Candida. This distant cousin of baker’s yeast is notorious for causing various types of thrush that can be a major nuisance, but it can also lead to an invasive infection that may, on occasion, prove fatal. In a study published in Nature Immunology, a Weizmann Institute of Science research team headed by Prof. Jakub Abramson uncovered a previously unknown defense mechanism employed by the immune system in fighting Candida infections. Immunologist Jan Dobeš from the Laboratory of Microbial Immunology at the our Department of Cell Biology also participated in the research.
Members of Jan Dobeš's team. Photo: archive of Jan Dobes


In Finland, Norway or a small village in Sardinia, Italy, patients with the Aire gene mutation are more likely to suffer from autoimmune diseases and yeast infections.

More details about the immunological mystery that Jan Dobeš and the team of prof.  Abramson at the prestigious Weizmann Institute of Science in Israel have managed to clarify, can be found here.  

Published: Jun 29, 2022 04:45 PM

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