Publikační přírůstky pracovníků katedry biochemie v roce 2011

Pracovníci katedry v roce 2011 úspěšně podali 38 publikací, ty jsou buď zveřejněné, nebo přijaté do tisku. Celkový součet impaktních faktorů těchto prací je 117.

1. Mizerovská J., Dračínská H., Frei E., Schmeiser H.H., Arlt V.M.., Stiborová M.:  Induction of biotransformation enzymes by the carcinogenic air pollutant 3-nitrobenzanthrone in liver, kidney and lung after intratracheal instillation in rats. Mutat. Res., 720, 34-41 (2011). IF₂₀₁₀ = 2.937.
2. Hendrychová T., Anzenbacherová E., Hudeček J, Skopalík J., Lange R., Hildebrandt P., Otyepka M., Anzenbacher P. Flexibility of human cytochrome P450 enzymes: molecular dynamics and spectroscopy reveal important function-related variations. Biochim. Biophys. Acta, 1814 (1), 58-68 (2011). IF₂₀₁₀ = 2.733.
3. Stiborová M., Rupertová M., Frei E.: Cytochrome P450- and peroxidase-mediated oxidation of anticancer alkaloid ellipticine dictates its anti-tumor efficiency. Biochim. Biophys. Acta, 1814 (1), 175-185 (2011). IF₂₀₁₀ = 2.733.
4. Levová K., Moserová M., Kotrbová V., Šulc M., Henderson C.J., Wolf C.R., Phillips D.H., Frei E., Schmeiser H.H., Mareš J., Arlt V.M., Stiborová M.: Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model. Toxicol. Sci,, 121, 43-56 (2011). IF₂₀₁₀ = 5.093.
5. Kosina P., Vacek J., Papouškova B., Stiborová M., Stýskala J., Cankař P., Vrublová E., Vostálová J., Šimánek V., Ulrichová J..: Identification of benzo[c]phenanthridine metabolites in human hepatocytes by liquid chromatography with electrospray ion-trap and quadrupole time-of-flight mass spectrometry J. Chromatography B, 879, 1077-1085 (2011).  IF₂₀₁₀ = 2.971.
6. Stiborová M., Poljaková J., Martínková E., Bořek-Dohalská L., Eckschlager T., Kizek R., Frei E.: Ellipticine cytotoxicity to cancer cell lines – a comparative study, Interdisc. Toxicol., 4, 98-105 (2011).
7. Stiborová M., Mareš J., Frei E., Arlt V.M., Martínek V., Schmeiser H.H.:  The human carcinogen aristolochic acid I is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases. Environ. Mol. Mutagen., 52, 448-459 (2011).  IF₂₀₁₀ = 3.493.
8. Hudcová T., Halecky M., Kozliak E., Stiborova M., Paca J.: Aerobic degradation of 2,4-dinitrotoluene by individual bacterial strains and mixed population in submerged cultures. J. Hazard. Mater., 192, 605-613 (2011).  IF₂₀₁₀ = 3.723.
9. Krizkova S., Zitka O., Masarik M., Adam V., Stiborova M., Eckschlager T., Hubalek J., Kizek R.: Clinical importance of matrix metalloproteinases. Bratisl. Med. Listy. 112, 435-440. IF₂₀₁₀ = 0.345.
10. Paca J., Halecky M., Hudcová T., Paca J. Jr, Stiborova M., Kozliak E.: Factors influencing the aerobic biodegradation of 2,4-dinitrotoluene in continuous packed bed reactors. J. Environ. Sci. Health A Tox. Hazard. Subst. Environ., 46, 1328-1337. IF₂₀₁₀ = 1.101.
11. Kotrbová V., Mrázová B., Moserová M., Martínek V., Hodek P., Hudeček J., Frei E., Stiborová M.: Cytochrome b₅ shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy. Biochem. Pharmacol., 82, 669-680 (2011). IF₂₀₁₀ = 4.889.
12. Arlt V.M., Levová K., Bárta F., Shi Z., Frei E., Schmeiser H.H., Nebert D.W., Phillips D.H., Stiborová M.: Role of CYP1A1 and CYP1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I: studies in Cyp1a(-/-) knockout mice. Chem. Res. Toxicol., 24, 1710-1719 (2011). IF₂₀₁₀ = 4.148.
13. Krizkova S., Zitka O., Adam V., Masarik M., Stiborova M., Eckschlager T., Babula P., Chavis G.J., Hubalek J., Kizek R.: Assays for determination of matrix metalloproteinases and their activity. TRAC-Trends in Analytical Chemistry, in press. IF₂₀₁₀ = 6.602.
14. Stiborová M., Mareš J., Levová K., Pavlíčková J., Bárta F., Hodek P., Frei E., Schmeiser H.H.: Role of cytochromes P450 in metabolism of carcinogenic aristolochic acid I: evidence of their contribution to aristolochic acid I detoxication and activation in rat liver. Neuro Endocrinol. Lett., in press. IF₂₀₁₀ = 1.621.
15. Hodek P., Křížková J., Frei E., Singh R., Arlt V.M., Stiborová M.: Impact of beta-naphthoflavone on genotoxicity of food-derived carcinogens. Neuro Endocrinol. Lett., in press. IF₂₀₁₀ = 1.621.
16. Turek M., Vilímková L., Kremláčková V., Páca J. Jr, Halecký M., Páca J., Stiborová M.: Isolation and partial characterization of extracellular NADPH-dependent phenol hydroxylase oxidizing phenol to catechol in Comamonas testosteroni., Neuro Endocrinol. Lett., in press. IF₂₀₁₀ = 1.621.
17. Poljakova J., Hrebackova J., Dvořákova M., Moserova M., Eckschlager T., Hrabeta J., Göttlicherova M., Kopejtkova B., Frei E., Kizek R., Stiborova M.: Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma. Neuro Endocrinol. Lett., in press. IF₂₀₁₀ = 1.621.
18. Martínek V., Kubickova B., Arlt V.M., Frei E., Schmeiser H.H., Hudecek J., Stiborova M.: Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases. Neuro Endocrinol. Lett., in press. IF₂₀₁₀ = 1.621.
19. Naiman K., Martínková M., Schmeiser H.H., Frei E., Stiborová M.: Human cytochromes P450 metabolize N-(2-methoxyphenyl)hydroxylamine, a metabolite of carcinogenic o-anisidine and o-nitroanisole, thereby dictating its genotoxicity.  Mutat. Res., 726, 160-168 (2011). IF₂₀₁₀ = 2.937.
20. Kizek R., Adam V., Hrabeta J., Eckschlager T., Smutny S., Burda J.V., Frei E., Stiborová M.:  Anthracyclines and ellipticines as DNA-damaging anticancer drugs; recent advances. Pharmacol. Ther., doi:10.1016/j.pharmthera.2011.07.006. IF₂₀₁₀ = 8.694.
21. Gumulec J., Masarik M., Krizkova S., Adam V., Hubalek J., Hrabeta J., Eckschlager T., Stiborová M., Kizek R.: Insight to physiology and pathology of Zinc(II) ions and their actions in breast and prostate carcinoma. Curr. Med. Chem., [Epub ahead of print]. PMID: 22050752.  IF₂₀₁₀ = 4.630.
22. Arlt V.M., Singh R., Stiborová M., Gamboa da Costa G., Frei E., Evans J., Farmer P.B.,  Wolf R.,  Henderson C.J., Phillips D.H.: Effect of hepatic cytochrome P450 enzyme activity deficiency on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adduct formation in Reductase Inducible Cre (RIC) mice. Drug. Metab. Dispos., [Epub ahead of print]. PMID: 21940903. IF₂₀₁₀= 3.716.
23. Procházka P., Libra A., Zemanová Z., Hřebačková J., Poljaková J., Hraběta J., Bunček M., Stiborová M., Eckschlager T.: Genetic and expression study of ellipticine resistant human neuroblastoma cells. Cancer Sci., [Epub ahead of print]. PMID: 22040216. IF₂₀₁₀ = 3.846.
24. Stiborová M., Levová K., Bárta F., Shi Z., Frei E., Schmeiser H.H., Nebert D.W., Phillips D.H., Arlt V.M.: Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2, Toxicol. Sci,, [Epub ahead of print]. PMID: 22086975. IF₂₀₁₀ = 5.093.
25. Kaplan O., Bezouška K., Malandra A., Veselá A.B., Petříčková A., Felsberg J., Rinágelová A., Křen V., Martínková L. 2011. Biotechnol. Lett. 33, 309-312. Genome mining for the discovery of new nitrilases in filamentous fungi. IF₂₀₁₀ = 1.676.
26. Kaplan O., Bezouška K., Plíhal O., Ettrich R., Kulik N., Vaněk O., Kavan D., Benada O., Malandra A., Šveda O., Veselá A.B., Rinágelová A., Slámová K., Cantarella M., Felsberg J., Dušková J., Dohnálek J., Kotík M., Křen V., Martínková L. 2011. BMC Biotechnol. 11, 2. Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10. IF₂₀₁₀ = 2.723
27. Rozbeský D., Kavan D., Chmelík J., Novák P., Vaněk O., Bezouška K. 2011. Protein Expr. Purif. 77, 178-184. High-level expression of soluble form of mouse natural killer cell receptor NKR-P1C(B6) in Escherichia coli. IF₂₀₁₀ = 1.849.
28. Vaněk O., Brynda J., Hofbauerová K., Kukačka Z., Pachl P., Bezouška K., Řezáčová P. 2011. Acta Cryst. F67, 498-503. Crystallization and diffraction analysis of b-N-acetylhexosaminidase from Aspergillus oryzae. IF₂₀₁₀ = 0.551
29. Sovová Z., Kopecký V. Jr., Pazderka T., Hofbauerová K., Rozbeský D., Vaněk O., Bezouška K., Ettrich R. 2011. J. Mol. Model 17, 1353-1370. Structural analysis of natural killer cell receptor protein 1 (NKR-P1) extracellular domains suggests a conserved long loop region involved in ligand specificity. IF₂₀₁₀ = 2.330.
30. Ryšlavá H., Kalendová A., Doubnerová V., Skočdopol P., Hodková A., Kukačka Z., Slámová K., Bojarová P., Pompach P., Kumar V., Kulik N., Ettrich R., Křen V., Bezouška K. 2011. FEBS J. 278, 2469-2484. Evolution of fungal b-N-acetylhexosaminidases understood through an enzymatic characterization combined with molecular modeling. IF₂₀₁₀ = 3.129
31. Drozdová A., Bojarová P., Křenek, K., Weignerová L., Henssen B., Elling L., Christensen H., Jensen H., Pelantová H., Kuzma M., Bezouška K., Krupová M., Adámek D., Slámová K., Křen V. 2011. Carbohydr. Res. 346, 1599-1609. Enzymatic synthesis of dimeric glycomimetic ligands of NK cell activation receptors. IF₂₀₁₀ = 2.166
32. Kolenko P., Rozbeský D., Vaněk O., Kopecký V.Jr., Hofbauerová K., Novák P., Pompach P., Hašek J., Skálová T., Bezouška K., Dohnálek J. 2011. J. Struct. Biol. 175, 434-441. Molecular structure of mouse activating NKR-P1 receptors. IF₂₀₁₀ = 3.925
33. Bojarová P., Slámová K., Křenek K., Gažák R., Kulik N., Ettrich R., Pelantová H., Kuzma M., Riva S., Adámek D., Bezouška K., Křen V. 2011. Adv. Synth. Catal. 353, 2409-2420. Charged hexosaminides as ligands of NK cell activation receptors – concerted chemoenzymatic synthesis. IF₂₀₁₀ = 5.447
34. Mrázek H., Benada O., Man P., Vaněk O., Křen V., Bezouška K., Weignerová L. 2011 Protein Expr. Purif. 81, 106-114. Facile production of Aspergillus niger a-N-acetylgalactosaminidase in yeast: dual activity and equal properties coupled with distinct quarternary structure. IF₂₀₁₀ = 1.849
35. Pechar M., Pola R., Laga R., Ulbrich K., Bednářová L., Maloň P., Seiglová I., Král V., Fábry M., Vaněk O. (2011) Biomacromolecules 12, 3645-3655. Coiled coil peptides as universal linkers for the attachment of recombinant proteins to polymeric therapeutics. IF₂₀₁₀ = 5.579
36. Petříčková A., Veselá A.B., Kaplan O., Kubáč D., Uhnáková B., Malandra A., Felsberg J., Rinágelová A., Weyrauch P., Křen V., Bezouška K., Martínková L. 2011. Appl. Microbiol. Biotechnol., corrected proof DOI 10.1007/s00253-011-3525-7. Purification and characterization of heterologously expressed nitrilases from filamentous fungi. IF₂₀₁₀ = 3.264
37. Kolenko P., Rozbeský D., Vaněk O., Bezouška K., Hašek J., Dohnálek J. 2011. Acta Crystallogr. F68, in press. Crystal structure of the H107R variant of the extracellular domain of mouse NKR-P1A at 2.3 A resolution. IF₂₀₁₀ = 0.551
38. Šulc, M., Fadrhonsová, I., Jelínková, M., Chudomelová, M., Felsberg, J., Olšovská, J. Determination of sibiromycin and its natural derivatives
    using new analytical and structural approaches Journal of Chromatography A 1218, 83-91(2011) IF₂₀₁₀ = 4.194

Výběr nejvýznamnějších publikací katedry za minulé roky i úplné přehledy publikační činnosti katedry biochemie jsou k uvedeny v sekci Publikace.