Postdoctoral position in Biochemistry of anaerobic parasitic protists

The applicants should have (i) a recent Ph.D. (the degree obtained no earlier than on 28th of March 2008), (ii) promising publication record and also be able to speak fluent English or Czech. After the initial contact with the group leader Ivan Hrdy hrdy@cesnet.cz. 
Please send signed CV and notarized proof of study to: Charles University in Prague, Faculty of Science, Department of HR, Albertov 6, 128 43 Prague 2, Czech Republic. Please sign the envelope with “POSTDOC II”. Alternatively, the documents can be sent to postdoc2@natur.cuni.cz The CV should contain list of publications (including the impact factor and the number citations) according to Web of Science. The contract will start on 1st of August 2012 or later and will be signed for 30 months. The position is funded by the European Social Fund in the Czech Republic and includes additional funds for the international mobility (up to 6 month). The monthly salary starts at 40 000 CZK.

Description

Characterization of putative redox proteins with unknown functions from Trichomonas vaginalis hydrogenosomes.

Research interests of our group focus on anaerobic protists, both parasitic and free-living, that possess unconventional mitochondria today known as hydrogenosomes, mitosomes, mitochondrion-related organelles and like. These organelles often harbor enzymes not seen in “classical” aerobic mitochondria, with some of them possibly involved in interactions with chemotherapeutics used to combat the infections caused by parasitic species of this group of diverse protists. We are interested in revealing the functions of such proteins, many of which appear to be acquired from anaerobic bacteria and have no counterparts in aerobic eukaryotic world.
Requirements: The successful candidate should have a strong background and hands-on experience in biochemistry, protein separation techniques, enzymology and standard methods of molecular cloning. Experience with cell cultivation techniques as well as with physico-chemical methods of protein characterization (redox titration, EPR) is advantageous.