Postdoctoral Researcher – Study of the mouse professional antigen presentation using MHCII-EGFP knock-in mouse

Postdoctoral position is available at the Department of Cell Biology to study the distribution and function of the professional antigen-presenting cells using the model MHCII-EGFP knock-in mouse. The ideal candidate for this position has strong background in immunology per se, has experience with the transgenic mouse models, advanced fluorescent imaging techniques and histological approaches.

The Laboratory is interested in membrane trafficking, antigen presentation in combination with the characterization of fungal and bacterial secondary metabolites and the establishment of new MRI probes.

Potential aims include:

- Dynamics of the dendritic cell and macrophage distribution during ontogeny and inflammation

- Adoptive cell transfers used to characterize homing mechanisms

- Transplantation models used to study dynamics of antigen-presenting cell migrations and activation

- Advanced imaging techniques for the characterization of secondary lymph organs in situ in vivo

Additional information on this position and research of the group may be obtained from Jan Černý (jan.cerny@natur.cuni.cz).