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Postdoctoral Researchers – Reaction mechanisms in organic chemistry and Organocatalytic asymmetric synthesis

Postdoctoral Researcher – Reaction mechanisms in organic chemistry:

The postdoctoral position is available for investigation of mechanisms of organic or organometallic reactions. Candidates should be interested in fundamentals of chemical reactivity and should have background in both organic as well as physical chemistry.

The Laboratory is interested in mechanisms of transition-metal catalyzed reactions and in fundamental questions about molecules and their properties. The research tools include mass spectrometry, computational chemistry, and synthetic chemistry. The candidate does not need to cover all methods; training is offered in each of the fields.

Potential aims include:

- Investigation of ionic species of given organometallic reactions using electro spray-ionization mass spectrometry, investigation of reactivity of the identified potential reaction intermediates

- Ion spectroscopy of reaction intermediates at European multi-user facilities with IR free-electron lasers

- Investigation of kinetics of the given reactions

- Suggestion of reaction mechanisms

Position is already occupied

 

Postdoctoral Researcher – Organocatalytic asymmetric synthesis:

The postdoctoral position is available for asymmetric chemical transformations via organocatalysis. Candidates should be interested in asymmetric synthesis, kinetic resolutions and should have background in synthetic organic chemistry.

The Laboratory is interested in organocatalytic asymmetric synthesis based on enamine, iminium catalysis and also H-bonding and PT catalysis. The research tools include general synthetic methodologies and purification techniques, NMR measurements, purification and characterization of products by HPLC and GC. The candidate does not need to cover all methods, training in each of the fields is offered.

Potential aims include:

- Development of new asymmetric organocatalytic tandem reactions using primary and secondary amine catalysis

- Application of developed chemical transformation into synthesis of biologically active compounds

- Suggestion of reaction mechanisms

- Preparation of new organic catalysts (polyfluorinated, hydrophilic, etc.)

References and additional information can be found at

http://www.orgchem.cz/vesely

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