Polycomb Repressive Complex 2 in plant growth and development – is there more to be found?
Mgr. Iva Mozgova, Ph.D.
(Centre Algatech, Institute of Microbiology CAS, CZ
+ University of South Bohemia, České Budějovice, CZ)
Polycomb Repressive Complexes (PRCs) are histone-modifying complexes that serve as major epigenetic regulators of developmental phase transitions in plants. The histone methyltrasferase PRC2 has been implicated in governing the seed-to-seedling transition by repressing embryo maturation program and preventing the reversion of the developmental phases during seedling establishment in Arabidopsis.
By mitigating the defects resulting from de-repression of late embryonic development in PRC2 mutants, we identify a novel function of PRC2 in modulating responses to ambient light conditions during seedling establishment in Arabidopsis. By combining transcriptomic, physiological and biochemical approaches, we aim to identify the upstream causative molecular mechanisms that trigger the observed phenotypic defects in mutant plants and establish PRC2 function during photomorphogenesis. Taken together, our results provide evidence supporting emerging roles of Polycomb repressive complexes in responses to environmental cues.
CV dostupné ZDE.
Pozvánka ke stažení ZDE.